Pharmacogenomics – Psychiatry

$150.00

Category:

About the Test

This panel provides a comprehensive analysis for 12 genes that have strong pharmacogenomic associations with medications used in the treatment of psychiatric disorders, including depression.

Overview

This panel provides a comprehensive analysis for 12 genes that have strong pharmacogenomic associations with medications used in the treatment of psychiatric disorders, including depression.

Genes

14 Genes

 ABCB1, ANKK1, COMT, CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP3A4, GRIK4, HTR2A, HTR2C, MTHFR, UGT2B15

Disorders
  • Depression
  • Psychiatric Disorders
Gene Function

https://www.genestreet.com/wp-content/uploads/2020/01/Pharmacogenomics-Gene-Function.pdf

Clinical Utility
  • Individualizing selection and dosage of medications prescribed for treatment of depression and other psychiatric disorders based on genetic variation
  • Identifying genetic variation in genes known to be associated with response and/or risk of toxicity with psychotropic medications
  • Evaluating patients who have failed therapy with selective serotonin reuptake inhibitors (SSRIs)
  • Evaluating patients with treatment-resistant depression
  • Predicting response time to improvement with SSRIs
When To Order

Patient is considering starting on or is currently on medication therapy for treatment of major depression or psychotropic disorders

Benefit To Patient
  • Determine the right medication for the patient based on their genptype
  • Avoid trial and error when prescribing medication to treat health problems
  • Avoid adverse drug reactions
Lab Method & Assay
  • PCR
Specimen Requirements

Buccal Swab

Turn Around Time

1-2 weeks

CPT Codes

81225, 81226

References